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About the Naka Reserach Group
私たちは有機化学と触媒に関わる諸問題の発見と解決，特に水や光を用いた有機合成のための触媒開発を中心に研究教育に取り組む，名古屋大学大学院理学研究科 野依特別研究室内の研究グループです．
News
2019.12.04 [受賞] 中助教が令和元年度 有機合成化学奨励賞を受賞することが決定しました．
2019.09.25 ジニトリルの水和反応に関する論文が Synlett 誌に掲載されました．
Naraoka and Naka, Synlett in press (2019).(Invited Cluster 'Metathesis beyond Olefins') [PDF] [解説]
2019.07.03 土居久志先生 (理化学研究所）の講演会を開催しました．
2019.06.04 水中脱水反応によるニトリルの合成に関する論文がOrg. Lett.誌に掲載されました．
Okabe, Naraoka, Isogawa, Oishi, Naka, Org. Lett. in press (2019).[PDF][解説]
2019.03.17 [メディア] 神田くんが Chem-Station で紹介されました (link)．
2019.03.16 [研究室紹介] 2019年度大学院説明会と研究室紹介を開催します (化学科HP)．
2019.02.02 [メディア] 神田くんと奈良岡さんの研究が Org. Process Res. Dev. (OPR&D) 誌で紹介されました (link)．
2019.01.05 シアノヒドリンの水和反応に関する論文が米国化学会誌に速報として掲載されました．
Kanda, Naraoka, Naka, J. Am. Chem. Soc. in press (2019).[PDF] [解説]
2018.12.18 Prof. Rinaldo Poli (University of Toulouse) の講演会を開催しました．
2018.11.22 光触媒による二級アミン合成に関する論文が Org. Lett. 誌に掲載されました．
Wang, Kobayashi, Arisawa, Saito, Naka, Org. Lett. in press (2019).[PDF]
2018.10.05 光触媒による医薬品合成に関する論文が ACS Sustainable Chem. Eng. 誌に掲載されました．
Wang, Jenkinson, Wheatley, Kuwata, Saito, Naka, ACS Sustainable C. E. in press (2018).[PDF][解説]
Contact
中 寛史 Hiroshi Naka
名古屋大学 助教
〒464-8602 名古屋市千種区不老町
名古屋大学 物質科学国際研究センター
野依記念物質科学研究館 503号室
052-789-5411
h_naka@nagoya-u.jp
http://noy.chem.nagoya-u.ac.jp/H_Naka-J/
Acknowledgemets to Our Supporters
私たちの研究教育に対する多大なるご支援を感謝いたします：
文部科学省，日本学術振興会
名古屋大学学術振興基金，名古屋大学男女共同参画センター
英国王立科学協会
岩谷科学技術財団
豊田理化学研究所
日揮実吉奨学会
量子化学探索研究所
戸部眞紀財団
市原国際奨学財団
野依フォーラム
吉田科学技術財団
Recent Publications
Transfer Hydration of Dinitriles to DicarboxamidesAsuka Naraoka and *Hiroshi Naka
Synlett 30, 1977–1980 (2019). (DOI: 10.1055/s-0039-1690026)
(Invited Cluster 'Metathesis beyond Olefins') [PDF] [解説]
Acceptor-Controlled Transfer Dehydration of Amides to Nitriles
Hiroyuki Okabe, Asuka Naraoka, Takahiro Isogawa, Shunsuke Oishi, and *Hiroshi Naka
Org. Lett. 21, 4767–4770 (2019). (DOI: 10.1021/acs.orglett.9b01657) [PDF] [解説]
Catalytic Transfer Hydration of Cyanohydrins to alpha-Hydroxyamides
Tomoya Kanda, Asuka Naraoka, and *Hiroshi Naka
J. Am. Chem. Soc. 141, 825−830 (2019). (DOI: 10.1021/jacs.8b12877) [PDF] [解説]
[Most Read Articles in Jan 2019]
(highlighted at Org. Process Res. Dev. 2019, 2, 114–121)
Pd-Catalyzed β-Selective C–H Arylation of Thiophenes with Triarylantimony Difluorides
Yuki Kitamura, Yuki Murata, Ayaka Oguri, Mio Matsumura, Naoki Kakusawa, *Hiroshi Naka, and *Shuji Yasuike
Asian J. Org. Chem. 8, 138−143 (2019).(DOI: 10.1002/ajoc.201800654) [PDF]
Lyu-Ming Wang, Kensuke Kobayashi, Mitsuhiro Arisawa, *Susumu Saito, and *Hiroshi Naka
Org. Lett., 21, 341–344 (2019). (DOI: 10.1021/acs.orglett.8b03271) [PDF] [解説]
(highlighted in front cover) (highlighted in Synfacts)
Photocatalytic N-Methylation of Amines over Pd/TiO2 for the Functionalization of Heterocycles and Pharmaceutical Intermediates
Lyu-Ming Wang, Kellie Jenkinson, Andrew E. H. Wheatley, Keiko Kuwata, Susumu Saito, and *Hiroshi Naka
ACS Sustainable Chem. Eng. 6, 15419–15424 (2018). (DOI: 10.1021/acssuschemeng.8b03855) [PDF][解説]
Copper(II) Bis(Diethyldithiocarbamate) Induces the Expression of Syndecan-4, a Transmembrane Heparan Sulfate Proteoglycan, via P38 MAPK Activation in Vascular Endothelial Cells
Takato Hara, Hiroko Tatsuishi, Tomomi Banno, Tomoya Fujie, Chika Yamamoto, Hiroshi Naka, and *Toshiyuki Kaji
Int. J. Mol. Sci. 19, 3302 (2018). (DOI: 10.3390/ijms19113302)
N-Alkylation of Functionalized Amines with Alcohols Using a Copper-Gold Mixed Photocatalytic System
Lyu-Ming Wang, Yuna Morioka, Kellie Jenkinson, *Andrew E. H. Wheatley, *Susumu Saito, and *Hiroshi Naka
Sci. Rep. 8, 6931. (2018). (DOI: 10.1038/s41598-018-25293-z) [Free PDF] [Blog]
Photocatalytic Hydrogenolysis of Allylic Alcohols for Rapid Access to Platform Chemicals and Fine Chemicals
Yuki Takada, Joaquim Caner, Hiroshi Naka, and *Susumu Saito
Pure Appl. Chem. 90, 167–174 (2018). (doi: https://doi.org/10.1515/pac-2017-0501)
A Fluorinated Cobalt(III) Porphyrin Complex for Hydroalkoxylation of Alkynes
Richiro Ushimaru, Takuho Nishimura, Toshiki Iwatsuki, *Hiroshi Naka
Chem. Pharm. Bull. 65, 1000–1003 (2017).[PDF]
Photocatalytic Transfer Hydrogenolysis of Allylic Alcohols on Pd/TiO2: A Shortcut to (S)-(+)-Lavandulol
Yuki Takada, Joaquim Caner, Kaliyamoorthy Selvam, Hiroshi Naka, *Susumu Saito
Chem. Eur. J. 23, 18025–18032 (2017). (DOI: 10.1002/chem.201704099)
Copper Diethyldithiocarbamate as an Inhibitor of Tissue Plasminogen Activator Synthesis in Cultured Human Coronary Endothelial Cells
Tomoya Fujie, Shiori Okino, Eiko Yoshida, Chika Yamamoto, *Hiroshi Naka, and *Toshiyuki Kaji
J. Toxicol. Sci. 42, 553–558 (2017) (doi: 10.2131/jts.42.553).
A Versatile Synthesis of Triarylantimony Difluorides by Fluorination of Triarylstibanes with Nitrosyl Tetrafluoroborate and Their Antitumor Activity
Yuki Kitamura, Mio Matsumura, Yuki Murata, Mizuki Yamada, Naoki Kakusawa, Motohiro Tanaka, Hiroyuki Okabe, *Hiroshi Naka, *Tohru Obata, and *Shuji Yasuike
J. Fluorine Chem. 199, 1–6 (2017). (doi: http://doi.org/10.1016/j.jfluchem.2017.04.004)
Dehydrogenation of Primary Aliphatic Alcohols by Au/TiO2 Photocatalysts
Masaki Shibata, Ryoko Nagata, Susumu Saito, and *Hiroshi Naka
Chem. Lett. 46, 580–582 (2017). (doi: 10.1246/cl.161195) [◀︎ Open Access] [Free PDF] [blog]
Selective Hydrogenation of Arenes to Cyclohexanes in Water Catalyzed by Chitin-Supported Ruthenium Nanoparticles
Yuna Morioka, Aki Matsuoka, Kellie Binder, Benjamin R. Knappett, Andrew E. H. Wheatley, and Hiroshi Naka
Catal. Sci. Technol. 6, 5801–5805 (2016) (doi: 10.1039/C6CY00899B).[◀︎ Open Access] [Free PDF] [blog]
Copper Diethyldithiocarbamate as an Activator of Nrf2 in Cultured Vascular Endothelial Cells
Tomoya Fujie, Masaki Murakami, Eiko Yoshida, Tadashi Tachinami, Yasuhiro Shinkai, Yasuyuki Fujiwara, Chika Yamamoto, Yoshito Kumagai, Hiroshi Naka, and Toshiyuki Kaji
J. Bio. Inorg. Chem. 21, 263–273 (2016). (doi: :10.1007/s00775-016-1337-z) [◀︎ Open Access] [Free PDF] [blog]
Induction of Metallothionein Isoforms by Copper Diethyldithiocarbamate in Cultured Vascular Endothelial Cells
Tomoya Fujie, Yukino Segawa, Tomoki Kimura, Yasuyuki Fujiwara, Chika Yamamoto, Masahiko Satoh, Hiroshi Naka, and Toshiyuki Kaji
J. Toxicol. Sci. 41, 225–232 (2016). (doi: 10.2131/jts.41.225) [◀︎ Open Access] [Free PDF]
Zinc Diethyldithiocarbamate as an Inducer of Metallothionein in Cultured Vascular Endothelial Cells
Tomoya Fujie, Yukino Segawa, Akane Uehara, Takehiro Nakamura, Tomoki Kimura, Eiko Yoshida, Chika Yamamoto, Masanobu Uchiyama, Hiroshi Naka, and Toshiyuki Kaji
J. Toxicol. Sci. 41, 217–224 (2016). (doi: 10.2131/jts.41.217) [◀︎ Open Access] [Free PDF]
N-Methylation of Amines with Methanol at Room Temperature
Vasily N. Tsarev, Yuna Morioka, Joaquim Caner, Qing Wang, Richiro Ushimaru, Akihiko Kudo, Hiroshi Naka, and Susumu Saito
Org. Lett. 17, 2530–2533 (2015). (doi: 10.1021/acs.orglett.5b01063)[blog]
Hydration of Nitriles to Amides by a Chitin- supported Ruthenium Catalyst
Aki Matsuoka, Takahiro Isogawa, Yuna Morioka, Benjamin R. Knappett, Andrew E. H. Wheatley, Susumu Saito, and Hiroshi Naka
RSC Adv. 5, 12152–12160 (2015). (doi:10.1039/C4RA15682J) [◀︎ Open Access] [Free PDF] [blog]
Why p-Cymene? Conformational Effect in Asymmetric Hydrogenation of Aromatic Ketones with a η6-Arene/Ruthenium(II) Catalyst
Aki Matsuoka, Christian A. Sandoval, Masanobu Uchiyama, Ryoji Noyori, and Hiroshi Naka
Chem. Asian J. 10, 112–115 (2015). (doi: 10.1002/asia.201402979 ) [◀︎ Open Access] [Free PDF] [blog]
Synthesis of Propylene from Renewable Allyl Alcohol by Photocatalytic Transfer Hydrogenolysis
Joaquim Caner, Zijun Liu, Yuki Takada, Akihiko Kudo, Hiroshi Naka, and Susumu Saito
Catal. Sci. Technol. 4, 4093–4098 (2014). (doi: 10.1039/C4CY00329B)[blog]
Activation of Cellular Defense Mechanism by Organic-Inorganic Hybrid Molecules
Tomoya Fujie, Hiroshi Naka, Chika Yamamoto, Yasuhiro Shinkai, Yoshito Kumagai, and Toshiyuki Kaji
Yakugaku Zasshi 134, 813−815 (2014). (doi: 10.1248/yakushi.14-00017-8) [Free PDF]
Hydration of Terminal Alkynes Catalyzed by Water-Soluble Cobalt Porphyrin Complexes
Tadashi Tachinami, Takuho Nishimura, Richiro Ushimaru, Ryoji Noyori, and Hiroshi Naka
J. Am. Chem. Soc. 135, 50−53 (2013). (doi: 10.1021/ja310282t) [blog]
Redox-Selective Generation of Aldehydes and H2 from Alcohols under Visible Light
Zijun Liu, Joaquim Caner, Akihiko Kudo, Hiroshi Naka, and Susumu Saito
Chem. Eur. J. 19, 9452–9456 (2013). (doi: 10.1002/chem.201301347) Highlighted in Synfacts [blog]
Acetals of N,N-Dimethylformamides: Ambiphilic Behavior in Converting Carbon Dioxide to Dialkyl Carbonates
Yuki Takada, Aki Matsuoka, Ya Du, Hiroshi Naka, and Susumu Saito
Chem. Lett., 42, 146–147 (2013). (doi: 10.1246/cl.2013.146) [blog]
Past News
2018.05.09 混合光触媒系による医薬関連アミン合成に関する論文がScientific Reports 誌に掲載されました．
Wang, Morioka, Jenkinson, Wheatley, Saito, Naka, Sci. Rep., 8, 6931 (2018).[Free PDF][解説]
2018.04.16 [受賞] Wang 君が日本化学会第98春季年会（2018）学生講演賞を受賞しました！
2018.04.01 [受賞] 中助教が豊田理研スカラーに選ばれました．
2018.03.26 特別企画 辻篤子先生が贈る日本語文章作成ワークショップ第2回を開催しました．
2017.11.09 アルキンのヒドロアルコキシ化反応に関する論文がChem Pharm Bull 誌に掲載されました．
Ushimaru, Nishimura, Iwatsuki, Naka, Chem. Pharm. Bull. 65, 1000–1003 (2017).[Free PDF]
2017.04.19 [受賞] 岡部君 (M2) が日本薬学会第137年会（2017）学生優秀発表者賞を受賞しました！
2017.04.18 [受賞] Wang 君が日本化学会第97春季年会（2017）学生講演賞を受賞しました！
2016.08.26 [受賞] 森岡さんが国際純正•応用化学会議 2016 (ISPAC 2016) で優秀講演賞を受賞！
メンバー
中 寛史
Alumni
王 呂鳴
森岡 優菜
岡部 弘幸
神田 智哉
永田 良子
岩月 俊樹
Kellie Binder
五十川 貴裕
柴田 将宣
森 清貴
Alan K. Kimura
松岡 亜季
M. Dahlkamp
岩田 眞輔
西村 拓歩
V. N. Tsarev
J. Caner
Z. Liu
牛丸 理一郎
鈴木 和彦
一色 絵利香
立浪 忠志
助教
Hiroshi Naka
email: h_naka@nagoya-u.jp
tel/fax: 052-789-5411
大学院生，2017- (文科省 科学技術人材育成補助金 研究支援員)
大学院生，2018-
大学院生，2018-
学部生，2019-
学部生，2019-
018
2019 Visitor (Boston University)
2019 MSc 自動車企業
2019 MSc 機械系企業
2018 PhD Ecolab R&D position
2018 MSc 理化学研究所 研究員
2018 MSc 素材系企業
2018 MSc 東京大学大学院生
2018 MSc 石油系企業
2017 MSc 化学系企業
2016 英国王立科学協会交換留学生
日本学術振興会サマープログラム交換学生
2016 MSc 化学系企業
2016 MSc 化学系企業
2016 MSc 化学系企業
2015 BSc ノースカロライナ大学大学院生
2015 PhD, 伊丹ERATO 研究推進主任
2014 Visitor, Muenster University
2014 MSc 化学系企業
2014 MSc 化学系企業
2014 日本学術振興会外国人特別研究員
2014 東京工業大学 研究員(岩澤研究室)
2013 RCMS 研究員
2013 MSc テキサス大学大学院生
2012 MSc 化学系企業
2011 BSc 北海道大学大学院生
2010 MSc 化学系企業
研究概要
単純物質や光を用いた有機合成のための触媒開発
有機化合物は医薬品や機能性分子，プラスチックなどの有用物質の生産に必要不可欠です．私達は水やメタノール，水素，二酸化炭素など，入手容易な小分子の変換を通して有機化合物を合成する新しい方法の開発を目指しています．具体的には有機化学と触媒化学に基づき新しい触媒プロセスをデザインすることを中心に，下記の研究課題に取り組んでいます．
（1）水移動型触媒反応の設計と応用
References
Transfer Hydration of Nitriles. J. Am. Chem. Soc. 141, 825–830 (2019). [PDF] [解説]
Transfer Dehydration of Amides. Org. Lett. 21, 4767–4770 (2019). [PDF] [解説]
Transfer Hydration of Dinitriles to Dicarboxamides. Synlett 30, 1977–1980 (2019). [PDF] [解説]
（2）単純物質の効率的変換を可能にする触媒の設計と応用
References
Hydration of Terminal Alkynes. J. Am. Chem. Soc. 135, 50−53 (2013). [解説]
Hydroalkoxylation of Alkynes. Chem. Pharm. Bull. 65, 1000–1003 (2017).[PDF]
Hydration of Nitriles to Amides. RSC Adv. 5, 12152–12160 (2015). [解説]
Hydrogenation of Arenes. Catal. Sci. Technol. 6, 5801–5805 (2016).[Free PDF] [解説]
Conformational Effect in Asymmetric Hydrogenation. Chem. Asian J. 10, 112–115 (2015). [Free PDF] [解説]
Converting Carbon Dioxide. Chem. Lett., 42, 146–147 (2013). [解説]
（3）半導体光触媒の特徴を利用した触媒反応開発
References
Self-Condensation of Primary Amines. Org. Lett., 21, 341–344 (2019). [PDF] [解説]
ACS Sustainable Chem. Eng. 6, 15419–15424 (2018). [PDF][Blog]
N-Alkylation of Functionalized Amines. Sci. Rep. 8, 6931. (2018). [Free PDF] [Blog]
Dehydrogenation of Aliphatic Alcohols. Chem. Lett. 46, 580–582 (2017). [Free PDF] [blog]
（4）ジチオカーバメート錯体を中心とした生体防御機能の解明に
資する分子群の創出
References
Inhibitor of Tissue Plasminogen Activator Synthesis. J. Toxicol. Sci. 42, 553–558 (2017).
Synthesis of Triarylantimony Difluorides and Their Antitumor Activity. J. Fluorine Chem. 199, 1–6 (2017).
Activator of Nrf2. J. Bio. Inorg. Chem. 21, 263–273 (2016). [Free PDF] [blog]
Induction of Metallothionein Isoforms. J. Toxicol. Sci. 41, 225–232 (2016). [Free PDF]
過去の研究：酸–塩基複合型試薬の設計と機能
論文リスト (PDF)
2019
Transfer Hydration of Dinitriles to Dicarboxamides
Asuka Naraoka and *Hiroshi Naka
Synlett 30, 1977–1980 (2019). (DOI: 10.1055/s-0039-1690026)
(Invited Cluster 'Metathesis beyond Olefins') [PDF] [解説]
Acceptor-Controlled Transfer Dehydration of Amides to Nitriles
Hiroyuki Okabe, Asuka Naraoka, Takahiro Isogawa, Shunsuke Oishi, and *Hiroshi Naka
Org. Lett. 21, 4767–4770 (2019). (DOI: 10.1021/acs.orglett.9b01657) [PDF] [解説]
Catalytic Transfer Hydration of Cyanohydrins to alpha-Hydroxyamides
Tomoya Kanda, Asuka Naraoka, and *Hiroshi Naka
J. Am. Chem. Soc. 141, 825−830 (2019). (DOI: 10.1021/jacs.8b12877) [PDF] [解説]
[Most Read Articles in Jan 2019]
(Tomoya highlighted at Chem-Station)
Pd-Catalyzed β-Selective C–H Arylation of Thiophenes with Triarylantimony Difluorides
Yuki Kitamura, Yuki Murata, Ayaka Oguri, Mio Matsumura, Naoki Kakusawa, *Hiroshi Naka, and *Shuji Yasuike
Asian J. Org. Chem. 8, 138−143 (2019).(DOI: 10.1002/ajoc.201800654) [PDF]
Lyu-Ming Wang, Kensuke Kobayashi, Mitsuhiro Arisawa, *Susumu Saito, and *Hiroshi Naka
Org. Lett., 21, 341–344 (2019). (DOI: 10.1021/acs.orglett.8b03271) [PDF] [解説]
(highlighted in front cover) (highlighted in Synfacts)
2018
Photocatalytic N-Methylation of Amines over Pd/TiO2 for the Functionalization of Heterocycles and Pharmaceutical Intermediates
Lyu-Ming Wang, Kellie Jenkinson, Andrew E. H. Wheatley, Keiko Kuwata, Susumu Saito, and *Hiroshi Naka
ACS Sustainable Chem. Eng. 6, 15419–15424 (2018). (DOI: 10.1021/acssuschemeng.8b03855) [PDF][解説]
Copper(II) Bis(Diethyldithiocarbamate) Induces the Expression of Syndecan-4, a Transmembrane Heparan Sulfate Proteoglycan, via P38 MAPK Activation in Vascular Endothelial Cells
Takato Hara, Hiroko Tatsuishi, Tomomi Banno, Tomoya Fujie, Chika Yamamoto, Hiroshi Naka, and *Toshiyuki Kaji
Int. J. Mol. Sci. 19, 3302 (2018). (DOI: 10.3390/ijms19113302)
N-Alkylation of Functionalized Amines with Alcohols Using a Copper-Gold Mixed Photocatalytic System
Lyu-Ming Wang, Yuna Morioka, Kellie Jenkinson, *Andrew E. H. Wheatley, *Susumu Saito, and *Hiroshi Naka
Sci. Rep. 8, 6931. (2018). (DOI: 10.1038/s41598-018-25293-z) [Free PDF] [解説]
Photocatalytic Hydrogenolysis of Allylic Alcohols for Rapid Access to Platform Chemicals and Fine Chemicals
Yuki Takada, Joaquim Caner, Hiroshi Naka, and *Susumu Saito
Pure Appl. Chem. 90, 167–174 (2018). (doi: https://doi.org/10.1515/pac-2017-0501) (invited conference paper)
2017
A Fluorinated Cobalt(III) Porphyrin Complex for Hydroalkoxylation of Alkynes
Richiro Ushimaru, Takuho Nishimura, Toshiki Iwatsuki, and *Hiroshi Naka
Chem. Pharm. Bull. 65, 1000–1003 (2017).[Free PDF]
Photocatalytic Transfer Hydrogenolysis of Allylic Alcohols on Pd/TiO2: A Shortcut to (S)-(+)-Lavandulol
Yuki Takada, Joaquim Caner, Kaliyamoorthy Selvam, Hiroshi Naka, and *Susumu Saito
Chem. Eur. J. 23, 18025–18032 (2017). (DOI: 10.1002/chem.201704099)
Copper Diethyldithiocarbamate as an Inhibitor of Tissue Plasminogen Activator Synthesis in Cultured Human Coronary Endothelial Cells
Tomoya Fujie, Shiori Okino, Eiko Yoshida, Chika Yamamoto, *Hiroshi Naka, and *Toshiyuki Kaji
J. Toxicol. Sci. 42, 553–558 (2017) (doi: 10.2131/jts.42.553).
A Versatile Synthesis of Triarylantimony Difluorides by Fluorination of Triarylstibanes with Nitrosyl Tetrafluoroborate and Their Antitumor Activity
Yuki Kitamura, Mio Matsumura, Yuki Murata, Mizuki Yamada, Naoki Kakusawa, Motohiro Tanaka, Hiroyuki Okabe, *Hiroshi Naka, *Tohru Obata, and *Shuji Yasuike
J. Fluorine Chem. 199, 1–6 (2017). (doi: http://doi.org/10.1016/j.jfluchem.2017.04.004)
Dehydrogenation of Primary Aliphatic Alcohols by Au/TiO2 Photocatalysts
Masaki Shibata, Ryoko Nagata, Susumu Saito, and *Hiroshi Naka
Chem. Lett. 46, 580–582 (2017). (doi: 10.1246/cl.161195) [◀︎ Open Access] [Free PDF] [解説]
2016
Selective Hydrogenation of Arenes to Cyclohexanes in Water Catalyzed by Chitin-Supported Ruthenium Nanoparticles
Yuna Morioka, Aki Matsuoka, Kellie Binder, Benjamin R. Knappett, *Andrew E. H. Wheatley, and *Hiroshi Naka
Catal. Sci. Technol. 6, 5801–5805 (2016) (doi: 10.1039/C6CY00899B).[Free PDF] [解説]
Copper Diethyldithiocarbamate as an Activator of Nrf2 in Cultured Vascular Endothelial Cells
Tomoya Fujie, Masaki Murakami, Eiko Yoshida, Tadashi Tachinami, Yasuhiro Shinkai, Yasuyuki Fujiwara, Chika Yamamoto, Yoshito Kumagai, *Hiroshi Naka, and *Toshiyuki Kaji
J. Bio. Inorg. Chem. 21, 263–273 (2016). (doi: :10.1007/s00775-016-1337-z) [Free PDF] [解説]
Induction of Metallothionein Isoforms by Copper Diethyldithiocarbamate in Cultured Vascular Endothelial Cells
Tomoya Fujie, Yukino Segawa, Tomoki Kimura, Yasuyuki Fujiwara, Chika Yamamoto, Masahiko Satoh, *Hiroshi Naka, and *Toshiyuki Kaji
J. Toxicol. Sci. 41, 225–232 (2016). (doi: 10.2131/jts.41.225) [◀︎ Open Access] [Free PDF]
Zinc Diethyldithiocarbamate as an Inducer of Metallothionein in Cultured Vascular Endothelial Cells
Tomoya Fujie, Yukino Segawa, Akane Uehara, Takehiro Nakamura, Tomoki Kimura, Eiko Yoshida, Chika Yamamoto, Masanobu Uchiyama, *Hiroshi Naka, and *Toshiyuki Kaji
J. Toxicol. Sci. 41, 217–224 (2016). (doi: 10.2131/jts.41.217) [◀︎ Open Access] [Free PDF]
2015
N-Methylation of Amines with Methanol at Room Temperature
Vasily N. Tsarev, Yuna Morioka, Joaquim Caner, Qing Wang, Richiro Ushimaru, Akihiko Kudo, Hiroshi Naka, and Susumu Saito
Org. Lett. 17, 2530–2533 (2015). (doi: 10.1021/acs.orglett.5b01063)[解説]
Hydration of Nitriles to Amides by a Chitin- supported Ruthenium Catalyst
Aki Matsuoka, Takahiro Isogawa, Yuna Morioka, Benjamin R. Knappett, Andrew E. H. Wheatley, Susumu Saito, and Hiroshi Naka
RSC Adv. 5, 12152–12160 (2015). (doi:10.1039/C4RA15682J) [◀︎ Open Access] [Free PDF] [解説]
Why p-Cymene? Conformational Effect in Asymmetric Hydrogenation of Aromatic Ketones with a η6-Arene/Ruthenium(II) Catalyst
Aki Matsuoka, Christian A. Sandoval, Masanobu Uchiyama, Ryoji Noyori, and Hiroshi Naka
Chem. Asian J. 10, 112–115 (2015). (doi: 10.1002/asia.201402979 ) [Free PDF] [解説]
2014
Synthesis of Propylene from Renewable Allyl Alcohol by Photocatalytic Transfer Hydrogenolysis
Joaquim Caner, Zijun Liu, Yuki Takada, Akihiko Kudo, Hiroshi Naka, and Susumu Saito
Catal. Sci. Technol. 4, 4093–4098 (2014). (doi: 10.1039/C4CY00329B)[解説]
Activation of Cellular Defense Mechanism by Organic-Inorganic Hybrid Molecules
Tomoya Fujie, Hiroshi Naka, Chika Yamamoto, Yasuhiro Shinkai, Yoshito Kumagai, and Toshiyuki Kaji
Yakugaku Zasshi 134, 813−815 (2014). (doi: 10.1248/yakushi.14-00017-8) [Free PDF]
2013
Hydration of Terminal Alkynes Catalyzed by Water-Soluble Cobalt Porphyrin Complexes
Tadashi Tachinami, Takuho Nishimura, Richiro Ushimaru, Ryoji Noyori, and Hiroshi Naka
J. Am. Chem. Soc. 135, 50−53 (2013). (doi: 10.1021/ja310282t) [解説]
Redox-Selective Generation of Aldehydes and H2 from Alcohols under Visible Light
Zijun Liu, Joaquim Caner, Akihiko Kudo, Hiroshi Naka, and Susumu Saito
Chem. Eur. J. 19, 9452–9456 (2013). (doi: 10.1002/chem.201301347) Highlighted in Synfacts [解説]
Acetals of N,N-Dimethylformamides: Ambiphilic Behavior in Converting Carbon Dioxide to Dialkyl Carbonates
Yuki Takada, Aki Matsuoka, Ya Du, Hiroshi Naka, and Susumu Saito
Chem. Lett., 42, 146–147 (2013). (doi: 10.1246/cl.2013.146) [解説]
論文リスト (PDF)
Naka Research Group
at The Noyori Laboratory, Nagoya University
